Epilepsy patients treated with vigabatrin exhibit reduced ocular blood flow
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چکیده
منابع مشابه
Epilepsy patients treated with vigabatrin exhibit reduced ocular blood flow.
BACKGROUND/AIM Reduced cerebral blood flow and decreased glucose metabolism have been identified in epilepsy patients receiving vigabatrin. It is likely that such a change may extend to the eye and may be linked to previously reported irreversible visual field defects. The aim of this study was to determine whether patients who have undergone anti-epileptic drug (AED) therapy with vigabatrin ha...
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PURPOSE Bilateral visual field constriction has been reported following the use of the antiepileptic drug (AED) vigabatrin. The incidence of retinal toxicity is variable and there are limited data in Asian populations. The authors report the results of ophthalmologic examination in Chinese patients taking this drug. METHODS The authors identified two groups of patients with refractory epileps...
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OBJECTIVE To assess early visual impairment related to vigabatrin prospectively in patients with and without visual symptoms. BACKGROUND Vigabatrin acts as an inhibitor of gamma-aminobutyric acid (GABA) transaminase. GABA-induced ion transport changes in the retinal pigment epithelium have been described. The electro-oculogram (EOG) is a clinical test that reflects photoreceptor and pigment e...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2003
ISSN: 0007-1161
DOI: 10.1136/bjo.87.1.96